Chloromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether
- Name Chloromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether
- CAS 26103-07-1
- Purity 99%
Product Details
Chloromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether GMP Manufacturer Global Trade 26103-07-1 with Fast Delivery
- Molecular Formula: C4H3ClF6O
- Molecular Weight: 216.511
- Vapor Pressure: 52.835mmHg at 25°C
- Refractive Index: 1.31
- Boiling Point: 94.979 °C at 760 mmHg
- Flash Point: 11.244 °C
- PSA： 9.23000
- Density: 1.488 g/cm3
- LogP: 2.69250
Chloromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether(Cas 26103-07-1) Usage
|
General Description |
Chloromethyl-1,1,1,3,3,3-hexafluoroisopropyl ether is a chemical compound that is often used as a solvent and reagent in various chemical reactions and processes. It is a fluorinated ether compound, containing carbon, hydrogen, chlorine, and fluorine atoms. This chemical is characterized by its highly fluorinated structure, which provides it with unique chemical and physical properties. It is commonly used as a solvent in organic synthesis, as well as in the production of various industrial chemicals and pharmaceuticals. Additionally, it can also be used as a reagent in the preparation of certain organic compounds, making it a valuable tool in organic chemistry research and development. However, it is important to handle and use this compound with caution, as it may pose risks to human health and the environment if not handled properly. |
InChI:InChI=1/C4H3ClF6O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2
26103-07-1 Relevant articles
An efficient and environmentally friendly synthesis of the inhalation anesthetic sevoflurane
Bieniarz, Christopher,Behme, Chris,Ramakrishna, Kornepati
, p. 99 - 102 (2000)
We report a new, high yield, single vess...
A safe and efficient process for the synthesis of the inhalation anesthetic sevoflurane
Ramakrishna, Kornpati,Behme, Chris,Schure, Ralph M.,Bieniarz, Christopher
, p. 581 - 584 (2000)
A novel method for the synthesis of 1,1,...
Method for synthesizing sevoflurane intermediate
-
Paragraph 0018-0041, (2019/10/01)
The invention discloses a method for syn...
Preparation method of chloromethyl hexafluoroisopropyl ether
-
Paragraph 0023; 0024; 0027; 0028, (2018/11/03)
The invention relates to a preparation m...
Method for synthesizing chloromethy-1,1,1,3,3,3-hexafluoroisopropyl ether
-
Paragraph 0018; 0019; 0020; 0021; 0022; 0023, (2016/12/22)
The invention discloses a method for syn...
Method for recycling sevoflurane impurity F(1)
-
Paragraph 0023; 0024; 0025; 0026; 0027; 0028-0038, (2017/07/22)
The invention discloses a method for rec...
26103-07-1 Process route
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-
50-00-0,30525-89-4,61233-19-0
formaldehyd
-
-
920-66-1
1,1,1,3',3',3'-hexafluoro-propanol
-
-
26103-07-1
1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether
| Conditions | Yield |
|---|---|
|
1,1,1,3',3',3'-hexafluoro-propanol;
With
aluminum (III) chloride;
In
acetonitrile;
at 0 - 10 ℃;
for 0.333333h;
Inert atmosphere;
formaldehyd;
In
acetonitrile;
at 15 ℃;
for 6h;
Temperature;
Inert atmosphere;
|
93.2%
|
|
With
aluminum (III) chloride; carbon dioxide;
at 32 - 36 ℃;
for 6h;
under 60006 - 63756.4 Torr;
Temperature;
Autoclave;
|
92.7%
|
|
1,1,1,3',3',3'-hexafluoro-propanol;
With
aluminum (III) chloride;
at -5 - 0 ℃;
for 0.5h;
Large scale;
formaldehyd;
at 35 ℃;
for 17h;
Large scale;
With
hydrogenchloride;
In
water;
at 0 - 15 ℃;
Large scale;
|
91.1%
|
|
With
thionyl chloride; sulfuric acid;
at 15 - 35 ℃;
Product distribution / selectivity;
|
84.4%
|
|
With
thionyl chloride; sulfuric acid;
at 15 - 35 ℃;
for 6h;
Product distribution / selectivity;
|
26.0 - 84.4 %Chromat.
|
|
With
thionyl chloride; sulfuric acid;
at 20 ℃;
for 6h;
Product distribution / selectivity;
|
26.0 - 84.4 %Chromat.
|
-
-
C7 H3 F13 O2
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-
26103-07-1
1,1,1,3,3,3-hexafluoroisopropyl chloromethyl ether
| Conditions | Yield |
|---|---|
|
With
1,3,5-Trioxan; aluminum (III) chloride;
at 10 ℃;
for 12h;
Temperature;
Concentration;
|
90.6%
|
|
With
hydrogenchloride; aluminum (III) chloride; formaldehyd;
In
water;
at 5 ℃;
for 6h;
Temperature;
|
26103-07-1 Upstream products
-
13171-18-1
1,1,1,3,3,3-hexafluoro-2-methoxypropane
-
110-88-3
1,3,5-Trioxan
-
920-66-1
1,1,1,3',3',3'-hexafluoro-propanol
-
28523-86-6
sevoflurane
26103-07-1 Downstream products
-
28523-86-6
sevoflurane
-
920-66-1
1,1,1,3',3',3'-hexafluoro-propanol
-
206756-25-4
2-Chloromethoxy-1,1,3,3,3-pentafluoro-propene
-
1357476-59-5
bis-1,3-(1,1,1,3,3,3-hexafluoroiso-propoxymethyl)imidazolium chloride
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