Sitafloxacin

Quality products?make an important contribution to long-term revenue and profitability. Bulk supply high purity Sitafloxacin 127254-12-0, Paid sample available

1.What is the Sitafloxacin ?

Sitafloxacin hydrate is the newest member (fourth generation) of the fluoroquinolone family of antibiotics that exhibits broad spectrum activity against many Gram-positive, Gramnegative, and anaerobic clinical isolates, including strains resistant to other fluoroquinolones. Since the launch of the first fluoroquinolone norfloxacin (patented in 1978), 20 other versions have made it to market with ciprofloxacin and levofloxacin experiencing the most prevalent usage. The mechanism of action involves inhibition of bacterial type II topoisomerases, both DNA gyrase and topoisomerase IV. By inhibiting these enzymes and preventing DNA supercoiling, cell division is disrupted leading to cell death. In Gram-negative bacteria, the primary target appears to be gyrase, whereas topoisomerase IV is involved in Gram-positive bacteria. Dual inhibition is attractive for widespread activity and avoidance of resistance as both encoding genes would have to acquire mutations.

2.What is the CAS number for Sitafloxacin ?

The CAS number of Sitafloxacin is 127254-12-0.

3.What are another words for Sitafloxacin ?

Synonyms?for?Sitafloxacin 127254-12-0:3-Quinolinecarboxylicacid,7-(7-amino-5-azaspiro[2.4]hept-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-,[1R-[1a(S*),2a]]-;DU 6859;DU 6859a;Gracevit;

4.What is Sitafloxacin (127254-12-0) used for?

Antibacterial (DNA-gyrase inhibitor).

InChI:InChI=1/C19H18ClF2N3O3/c20-14-15-8(17(26)9(18(27)28)5-25(15)12-4-10(12)21)3-11(22)16(14)24-6-13(23)19(7-24)1-2-19/h3,5,10,12-13H,1-2,4,6-7,23H2,(H,27,28)/t10-,12+,13+/m0/s1

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5.Buy Sitafloxacin with the best price .

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