3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate
- Name 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate
- CAS 51-60-5
- Purity 99%
Product Details
Quality products?make an important contribution to long-term revenue and profitability. Factory Sells Best Quality 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate 51-60-5 with steady supply
1.What is the 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate ?
Used in Pharmaceutical Industry:
Neostigmine methylsulfate is used as a pharmaceutical compound for the treatment of myasthenia gravis and Ogilvie syndrome. It functions by inhibiting the enzyme acetylcholinesterase, which in turn increases the levels of endogenous acetylcholine. This increase in acetylcholine levels helps restore muscle action potentials and improves the symptoms of the mentioned conditions.
Used in Veterinary Medicine:
In a rat model of knee joint inflammation, intrathecal administration of neostigmine (2-30 μg) has been shown to dose-dependently increase the latency of paw withdrawal in response to thermal and mechanical stimuli. This suggests that neostigmine can be used as an analgesic agent in veterinary medicine to manage pain and inflammation in animals.
Used in Research Applications:
Neostigmine methylsulfate is also used in research settings to study the effects of acetylcholinesterase inhibition on various physiological processes. It can be employed in experiments involving neuromuscular junction function, pain perception, and other related areas.
Brand Name:
The brand name for 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate is Prostigmine (ICN).
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16088-19-0
norneostigmine
-
-
77-78-1
dimethyl sulfate
-
-
51-60-5
neostigmine methyl sulfate
| Conditions | Yield |
|---|---|
|
In
acetone;
at 20 ℃;
four neck round bottom flask;
|
85%
|
|
In
tetrahydrofuran;
at 20 ℃;
for 8h;
|
70%
|
|
With
acetone;
|
|
|
With
acetone;
|
-
-
19962-04-0
Dimethylcarbaminsaeure-3-aminophenylester
-
-
77-78-1
dimethyl sulfate
-
-
51-60-5
neostigmine methyl sulfate
| Conditions | Yield |
|---|---|
|
With
calcium carbonate;
In
acetone;
at 25 - 30 ℃;
Reagent/catalyst;
|
84.6%
|
2.What is the CAS number for 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate ?
The CAS number of 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate is 51-60-5.
More information of 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate 51-60-5 are:
|
CAS?Number |
51-60-5 |
|
Melting Point |
175-177 °C(lit.) |
|
Boiling Point |
457oC |
|
HS CODE |
29242990 |
|
PSA |
104.35000 |
|
LogP |
2.11750 |
3.What are another words for 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate ?
Synonyms?for?3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate 51-60-5:Prostigmin methyl sulfate;Benzenaminium,3-[[(dimethylamino)carbonyl]- oxy]-N,N,N-trimethyl-,methyl sulfate;AR-32;Normastigmin;Polstigmine;Stigmanol methyl sulfate;(3-Hydroxyphenyl)trimethylammonium methyl sulfate dimethylcarbamic ester;[3-(Dimethylcarbamoyl)oxyphenyl]trimethylammonium methyl sulfate;Synthostigmine methyl sulfate;[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium; sulfonatooxymethane;Vagostigmin;Philostigmin methyl sulfate;[3-(dimethylcarbamoyloxy)phenyl]-trimethyl-azanium; sulfooxymethane;Dimethylcarbamic ester of 3-oxyphenyltrimethylammonium methylsulfato;Leostigmine methyl sulfate;Synstigmine;Proserine methyl sulfate;Proserine;Neostigmine monomethyl sulfate;[3-(Dimethylcarbamoxy)phenyl]trimethylammonium methyl sulfate;Neostigmine methosulfate;Syntostigmin (injection);SB-23;Prostigmine methyl sulfate;Kirkstigmine;Proserin;Ammonium, [3-(dimethylcarbamoyloxy)phenyl]trimethyl-, methyl sulfate;Prostigmin (TN);neostigmine metilsulfate;
4.What is the molecular formula of 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate?
The chemical formula of ?3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate is?C13H22N2O6S which containing 13 Carbon atoms,22 Hydrogen atoms,2 Nitrogen atoms,6 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate?is 334.393.
5.What is 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate (51-60-5) used for?
Neostigmine is a reversible inhibitor of acetylcholinesterase (AChE; Kd = 260 μM). In a rat model of knee joint inflammation, intrathecal administration of neostigmine (2-30 μg) increases endogenous acetylcholine levels and dose-dependently increases the latency of paw withdrawal in response to thermal and mechanical stimuli (ED50s = 6.6 and 3.5 μg, respectively). Neostigmine (5 μg, i.p.) restores muscle action potentials in mice with a thymopoietin-induced neuromuscular block. Formulations containing neostigmine have been used in the treatment of myasthenia gravis and Ogilvie syndrome.
InChI:InChI=1/C12H19N2O2.CH4O4S/c1-13(2)12(15)16-11-8-6-7-10(9-11)14(3,4)5;1-5-6(2,3)4/h6-9H,1-5H3;1H3,(H,2,3,4)/q+1;
Relevant articles related to 3-[[(Dimethylamino)carbonyl]oxy]-N,N,N-trimethylbenzenaminium methyl sulfate:
|
Article |
Source |
|
HIGHLY CHEMOSELECTIVE REACTIONS IN PRESENCE OF AROMATIC AMINO GROUPS |
- Page/Page column 32, (2017/11/06) |
|
Synthesis of some new neostigmine methyl sulphates and related compounds |
Rittner,Barbarini,Hoeehr , p. 181 - 182 (2007/10/03) |
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