OMIGAPIL

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OMIGAPIL

  • Name OMIGAPIL
  • CAS 181296-84-4
  • Purity 99%
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Product Details

Factory supply OMIGAPIL 181296-84-4 with sufficient stock and high standard

  • Molecular Formula: C19H17NO
  • Molecular Weight: 275.3444
  • Vapor Pressure: 7.07E-07mmHg at 25°C 
  • Boiling Point: 408.3°C at 760 mmHg 
  • Flash Point: 120°C 
  • PSA: 12.47000 
  • Density: 1.127g/cm3 
  • LogP: 3.89790 

OMIGAPIL(Cas 181296-84-4) Usage

General Description

Omigapil is a synthetic compound that has shown promise in the treatment of muscle degeneration and weakening in conditions such as muscular dystrophy. It works by inhibiting the activity of an enzyme known as 15-lipoxygenase (15-LOX), which is involved in promoting inflammation and muscle damage. By reducing the levels of 15-LOX, omigapil can help to protect muscle cells from damage and improve their overall function. This potential therapeutic effect makes omigapil an important target for further research and development in the treatment of muscle degenerative diseases.

InChI:InChI=1/C19H17NO/c1-3-12-20(2)14-16-13-15-8-4-6-10-18(15)21-19-11-7-5-9-17(16)19/h1,4-11,13H,12,14H2,2H3

181296-84-4 Relevant articles

COUMPOUNDS MODULATING THE ACTIVITY OF GAPDH AND/OR IAMT

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Page 38, (2010/02/06)

Novel compounds and their use for modula...

Anti-neurodegeneratively active 10-aminoaliphatyl-dibenzi ?b,f! oxepines

-

, (2008/06/13)

Base-substituted debenz?b,f!oxepines of ...

181296-84-4 Process route

methyl(propargyl)amine
35161-71-8

methyl(propargyl)amine

10-(hydroxymethyl)dibenz[b,f]oxepin

10-(hydroxymethyl)dibenz[b,f]oxepin

10-(N-methyl-N-propargyl-amino)methyldibenz[b,f]oxepine
181296-84-4

10-(N-methyl-N-propargyl-amino)methyldibenz[b,f]oxepine

Conditions
Conditions Yield
10-(hydroxymethyl)dibenz[b,f]oxepin; With 4-methyl-morpholine; methanesulfonyl chloride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 3h;
methyl(propargyl)amine; In DMF (N,N-dimethyl-formamide); at 40 - 60 ℃; for 1.5h;
10-(N-methyl-N-propargyl-amino)methyldibenz[b,f]oxepine
181296-84-4

10-(N-methyl-N-propargyl-amino)methyldibenz[b,f]oxepine

Conditions
Conditions Yield

181296-84-4 Upstream products

  • 35161-71-8
    35161-71-8

    methyl(propargyl)amine

181296-84-4 Downstream products

  • 634202-78-1
    634202-78-1

    dibenzo[b,f]oxepine-10-ylmethyl-methyl-prop-2-ynyl-amine monomaleic acid salt

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