3-Azido-3-deoxy-5-O-triphenylmethylthymidine

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3-Azido-3-deoxy-5-O-triphenylmethylthymidine

  • Name 3-Azido-3-deoxy-5-O-triphenylmethylthymidine
  • CAS 29706-84-1
  • Purity 99%
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1.What is the 3-Azido-3-deoxy-5-O-triphenylmethylthymidine ?

Used in Pharmaceutical Research:
3-Azido-3-deoxy-5-O-triphenylmethylthymidine is used as a nucleotide analog for its antiviral and antitumor properties due to its ability to inhibit DNA and RNA synthesis. This leads to the disruption of viral replication and the proliferation of cancer cells, offering potential therapeutic benefits in treating viral infections and various types of cancer.
Used in Drug Development:
3-Azido-3-deoxy-5-O-triphenylmethylthymidine's triphenylmethyl group enhances its stability and bioavailability, making 3-Azido-3-deoxy-5-O-triphenylmethylthymidine a promising candidate for further pharmaceutical development. Its potential applications include the creation of new antiviral and antitumor drugs, as well as the improvement of existing treatments through enhanced efficacy and reduced side effects.
Used in Antiviral Applications:
3-Azido-3-deoxy-5-O-triphenylmethylthymidine is used as an antiviral agent for its ability to inhibit viral replication by disrupting DNA and RNA synthesis. This makes it a valuable tool in the development of treatments for a wide range of viral infections, including those caused by RNA and DNA viruses.
Used in Antitumor Applications:
In the field of oncology, 3-Azido-3-deoxy-5-O-triphenylmethylthymidine is used as an antitumor agent, targeting the inhibition of cancer cell proliferation by interfering with DNA synthesis. Its potential to disrupt the growth and spread of cancer cells positions it as a candidate for the development of novel cancer therapies.
Used in Biochemistry and Molecular Biology Research:
3-Azido-3-deoxy-5-O-triphenylmethylthymidine's unique structure and properties also make it a valuable tool in biochemical and molecular biology research. It can be used to study the mechanisms of DNA and RNA synthesis, as well as the effects of nucleotide analogs on various biological processes. This research can contribute to a deeper understanding of the molecular basis of viral infections and cancer, and may lead to the discovery of new therapeutic targets and strategies.

1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine
42214-24-4

1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-ribopentofuranosyl)thymine

5'-O-trityl-2,3'-anhydrothymidine
25442-42-6

5'-O-trityl-2,3'-anhydrothymidine

1-(3-Azido-2,3-dideoxy-5-O-trityl-β-D-threo-pentofuranosyl)thymine
66503-47-7

1-(3-Azido-2,3-dideoxy-5-O-trityl-β-D-threo-pentofuranosyl)thymine

1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
29706-84-1

1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine

Conditions
Conditions Yield
With lithium azide; In N,N-dimethyl-formamide; at 100 ℃; for 5h;
5%
15%
48%
With lithium azide; In N,N-dimethyl-formamide; at 150 ℃; for 0.5h;
25%
32%
25%
1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-threo-pentofuranosyl)thymine
104218-44-2

1-(2-deoxy-3-O-methanesulfonyl-5-O-trityl-β-D-threo-pentofuranosyl)thymine

1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine
29706-84-1

1-(3-azido-2,3-deoxy-5-O-trityl-β-D-erythro-pentofuranosyl)thymine

Conditions
Conditions Yield
With sodium azide; In ethylene glycol; at 120 ℃; for 0.75h;
87%
With lithium azide; In N,N-dimethyl-formamide; at 80 ℃; for 4h;

2.What is the CAS number for 3-Azido-3-deoxy-5-O-triphenylmethylthymidine ?

The CAS number of 3-Azido-3-deoxy-5-O-triphenylmethylthymidine is 29706-84-1.

More information of 3-Azido-3-deoxy-5-O-triphenylmethylthymidine 29706-84-1 are:

CAS?Number

29706-84-1

Melting Point

103-104 °C(Solv: toluene (108-88-3))

PSA

123.33000

LogP

4.68516

3.What are another words for 3-Azido-3-deoxy-5-O-triphenylmethylthymidine ?

Synonyms?for?3-Azido-3-deoxy-5-O-triphenylmethylthymidine 29706-84-1:Thymidine,3'-azido-3'-deoxy-5'-O-trityl- (8CI); 3'-Azido-3'-deoxy-5'-O-tritylthymidine

4.What is the molecular formula of 3-Azido-3-deoxy-5-O-triphenylmethylthymidine?

The chemical formula of ?3-Azido-3-deoxy-5-O-triphenylmethylthymidine is?C29H27 N5 O4 which containing 29 Carbon atoms,27 Hydrogen atoms,5 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of??3-Azido-3-deoxy-5-O-triphenylmethylthymidine?is 509.564.

5.What is 3-Azido-3-deoxy-5-O-triphenylmethylthymidine (29706-84-1) used for?

3-Azido-3-deoxy-5-O-triphenylmethylthymidine is a chemical compound derived from thymidine, featuring a triphenylmethyl group at the 5-O position and an azido group at the 3 position on the deoxyribose ring. This modification endows the compound with unique antiviral and antitumor properties, making it a valuable subject in nucleotide analogs research.

Relevant articles related to 3-Azido-3-deoxy-5-O-triphenylmethylthymidine:

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