Riluzole

Good factory supply good Riluzole 1744-22-5 We provide high quality Riluzole (CAS 1744-22-5), at a very affordable prices to our customers.

1.What is the Riluzole ?

Rilutek was launched in Germany, the UK and US (orphan drug status) for treatment of amyotrophic lateral sclerosis (ALS) and is the first drug approved for this indication. A one step synthesis from 4-(trifluoromethoxy)aniline provides a supply of the compound. The source of its neuroprotective and anticonvulsant activity is not clearly understood. It antagonizes excitatory amino acids and blocks presynaptic release of glutamate, is an antagonist of NMDA-induced acetylcholine release and inhibited glutamate and quisqualate induced increases in cGMP but does not bind to NMDA or Kainic receptors. Rilutek has no affinity for glutamate, GABAbenzodiazepine, glycine and adenosine receptors. It easily crosses the blood brain barrier and depresses glutamatergic neurotransmission, stabilizes voltagedependent Na channels in their inactive form and activates G-protein dependent processes.

A neuroprotective agent. A glutamate release inhibitor. An anticonvulsant

2.What is the CAS number for Riluzole ?

The CAS number of Riluzole is 1744-22-5.

More information of Riluzole 1744-22-5 are:

3.What is the molecular formula of Riluzole ?

The chemical formula of?Riluzole is C8H5F3N2OS which containing 8 Carbon atoms,5 Hydrogen atoms,3 Fluorine atoms,2 Nitrogen atoms,1 Oxygen atoms and 1 Sulfur atoms,and the molecular weight, and the molecular weight of Riluzole is 234.202

4.What is Riluzole(1744-22-5)used for?

Rilutek was launched in Germany, the UK and US (orphan drug status) for treatment of amyotrophic lateral sclerosis (ALS) and is the first drug approved for this indication. A one step synthesis from 4-(trifluoromethoxy)aniline provides a supply of the compound. The source of its neuroprotective and anticonvulsant activity is not clearly understood. It antagonizes excitatory amino acids and blocks presynaptic release of glutamate, is an antagonist of NMDA-induced acetylcholine release and inhibited glutamate and quisqualate induced increases in cGMP but does not bind to NMDA or Kainic receptors. Rilutek has no affinity for glutamate, GABAbenzodiazepine, glycine and adenosine receptors. It easily crosses the blood brain barrier and depresses glutamatergic neurotransmission, stabilizes voltagedependent Na channels in their inactive form and activates G-protein dependent processes.

InChI:InChI=1/C8H5F3N2OS.ClH/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5;/h1-3H,(H2,12,13);1H

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5.Good factory supply good Riluzole 1744-22-5

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